Explore Our Publications

  • El Bitar L, Sarraf F, Nafeh P, Habib A, Mahfoud I, Yazbeck A, Younes M, Wex B, Rizk S. 2025. A review of Farnesiferol C: From molecular insights to anticancer potential and emerging therapeutic applications. Biomed Pharmacother. 2025 Dec;193:118725. https://doi.org/10.1016/j.biopha.2025.118725 (Q1).
  • Nafeh P, Nafeh G, Younes M, Chaaban A, El Bitar L, Ibrahim JN, Kobeissy H, Rizk S. 2025. Urtica dioica leaf infusion enhances cisplatin-induced apoptosis in ovarian cancer cells in vitro. BMC Complement Med Ther 25, 304 (2025). https://doi.org/10.1186/s12906-025-05053-z (Q1).
  • Wanes D, Al Aoua S, Shammas H, Walters F, Das A, Rizk S, and Naim H.Y. 2024. Rosa canina L. Methanol Extract and Its Component Rutin Reduce Cholesterol More Efficiently than Miglustat in Niemann–Pick C Fibroblasts. International Journal of Molecular Sciences 2024, 25 (21), 11361. https://doi.org/10.3390/ijms252111361. (Q1).
  • Abi Akl M, Hajj R, Jamati G, Karam L, Ibrahim JN, Kobeissy PH, Younes M, Rizk S. 2024. Protective Effects of Nettle Tea on SKOV-3 Ovarian Cancer Cells Through ROS Production, Apoptosis Induction, and Motility Inhibition Without Altering Autophagy. Foods, 2024 Oct 21;13(20):3336. https://doi.org/10.3390/foods13203336 (Q1).
  • Younes M, El Hage M, Shebaby W, Al Toufaily S, Ismail J, Naim HY, Mroueh M, Rizk S. 2024. The molecular anti-metastatic potential of CBD and THC from Lebanese Cannabis via apoptosis induction and alterations in autophagy. Scientific Reports 14, 25642 (2024). https://doi.org/10.1038/s41598-024-76340-x (Q1).
  • Abi Sleiman M, Younes M, Hajj R, Salameh T, Abi Rached S, Abi Younes R, Daoud L, Doumiati JL, Frem F, Ishak R, Medawar C, Naim HY*, Rizk S. 2024. Urtica dioica: Anticancer Properties and Other Systemic Health Benefits from In Vitro to Clinical Trials. International Journal of Molecular Sciences, 2024 Jul 8;25(13):7501. doi: 10.3390/ijms25137501. (Q1).
  • Younes M, Loubnane G, Sleiman C, Rizk S. 2024. Tocotrienol isoforms: The molecular mechanisms underlying their effects in cancer therapy and their implementation in clinical trials. Journal of Integrative Medicine vol 22 (1); 1-11 (WoS IF=3.95, Q1).
  • Zamfir-Taranu A, Löscher BS, Husein DM, Hoter A, Garcia-Etxebarria K, Etxeberria U, Gayoso L, Mayr G, Nilholm C, Gustafsson RJ, Ozaydin O, Zheng T, Esteban-Blanco C, Bozzarelli I, Bonfiglio F, Rizk S, Franke A, Bujanda L, Naim HY, D’Amato M. 2024. Sucrase-isomaltase genotype and response to a starch-reduced and sucrose-reduced diet in IBS-D patients. Gut 2024; 73 (4); 706-708. https://gut.bmj.com/content/gutjnl/73/4/706.2.full.pdf (WOS IF=31.8, Q1).
  • Nafeh, G., Abi Akl, M., Samarani, J., Bahous, R., Al Kari, G., Younes, M., Sarkis, R. and Rizk, S., 2023. Urtica dioica leaf infusion enhances the sensitivity of triple-negative breast cancer cells to cisplatin treatment. Pharmaceuticals, 16(6); 780. https://www.mdpi.com/1424-8247/16/6/780 (WoS IF=4.2, Q2).
  • El Samarji M, Younes M, El Khoury M, Haykal T, Elias N, Gasilova N, Menin L, Houri A, Machaka-Houri N, Rizk S. 2023. The antioxidant and pro-apoptotic effects of Sternbergia clusiana bulb ethanolic extract on triple negative and estrogen-dependent breast cancer cells in vitro. Plants, 12(3), 529; https://doi.org/10.3390/plants12030529 (WoS IF=4.66, Q1).
  • Husein D.M, Rizk S, Hoter A, Wanes D, D'Amato M, Naim H.Y. 2022. Severe pathogenic variants of intestinal sucrase-isomaltase interact avidly with the wild type enzyme and negatively impact its function and trafficking. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1868(11), p.166523. https://doi.org/10.1016/j.bbadis.2022.166523 (WoS IF=6.6, Q1)
  • Younes M, Mardirossian R, Rizk L, Fazlian T, Khairallah J. P, Sleiman C, Naim HY, Rizk, S. 2022. The Synergistic Effects of Curcumin and Chemotherapeutic Drugs in Inhibiting Metastatic, Invasive and Proliferative Pathways. Plants, 11(16), 2137. https://doi.org/10.3390/plants11162137 (WoS IF=4.66, Q1)
  • Kabbani S, Karkoulian S, Balozian P, Rizk S. 2022. The Impact of Ethical Leadership, Commitment and Healthy/Safe Workplace Practices toward Employee Attitude to COVID-19 Vaccination/Implantation in the Banking Sector in Lebanon. Vaccines, 10(3), 416; https://doi.org/10.3390/vaccines10030416 (WoS IF=4.4).
  • Idriss M, Younes M, Abou Najem S, Hodroj M, Fakhoury R, Rizk S. 2022. Gamma-tocotrienol Synergistically Promotes the Anti-proliferative and Pro-apoptotic Effects of Etoposide on Breast Cancer Cell Lines. Current Molecular Pharmacology, 15 (7), 980-986. https://doi.org/10.2174/1874467215666220131095611. (WoS IF=3.86/Q2).
  • Haykal T, Younes M, El Khoury M, Ammoury C, Tannous S, Hodroj MH, Sarkis R, Gasilova N, Menin L, Rizk S. 2021. The pro-apoptotic properties of a phytonutrient rich infusion of A. cherimola leaf extract on AML cells. Biomedicine and Pharmacotherapy, 140 (2021), 111592; https://doi.org/10.1016/j.biopha.2021.111592 (WoS IF=7.4/Q1; Scopus: Q1 Medicine, Pharmacotherapy, SJR=1.05).
  • Husein D, Rizk S, Naim HY. 2021. Differential Effects of Sucrase-Isomaltase Mutants on Its Trafficking and Function in Irritable Bowel Syndrome: Similarities to Congenital Sucrase-Isomaltase Deficiency. Nutrients 13(1), 9; https://doi.org/10.3390/nu13010009 (WoS IF=6.7/Q1; Scopus: Q1 Food Science, Nutrition and Diitetics, SJR=1.33).
  • Wanes D, Toutounji M, Sebai H, Rizk S, Naim HY. Rosa canina L. 2021. Can Restore Endoplasmic Reticulum Alterations, Protein Trafficking and Membrane Integrity in a Dextran Sulfate Sodium-Induced Inflammatory Bowel Disease Phenotype. Nutrients, 13(2), 441; https://doi.org/10.3390/nu13020441 (WoS IF=6.7/Q1; Scopus: Q1 Food Science, Nutrition and Diitetics, SJR=1.33).
  • Chahine JB, Haykal T, Al Hageh C, Rizk S, Khnayzer R, Khalil C. 2021. E-cigarette liquids and aerosols induced DNA damages and necrosis in dynamically exposed A549 cells. Chemosphere, 263 (127874); https://doi.org/10.1016/j.chemosphere.2020.127874 (WoS IF=5.78/Q1; Scopus: Q1 Health and Toxicology, Q1 Medicine, SJR=1.53).
  • Younes M, Ammoury C, Haykal T, Nasr L, Sarkis R, Rizk S. 2020. The selective anti-proliferative and pro-apoptotic effect of A. cherimola on MDA-MB-231 Breast Cancer cell line. BMC Complementary and Alternative Medicine (currently BMC Complementary Medicine and Therapies), 20: 343 https://doi.org/10.1186/s12906-020-03120-1 (WoS IF=2.83/Q1; Scopus: Q1 Complementary and Alternative Medicine, SJR=0.74).
  • Tannous S, Haykal T, Dhainy J, Hodroj MH, Rizk S. 2020. The Anti-Cancer Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells. Biomedicine and Pharmacotherapy, 132 (110884); https://doi.org/10.1016/j.biopha.2020.110884 (WoS IF=7.4/Q1; Scopus: Q1 Medicine, Pharmacotherapy, SJR=1.05).
  • Hodroj MH, Al Bast NAH, Taleb R, Borjac J, Rizk S. 2020. Nettle Tea Inhibits Growth of Acute Myeloid Leukemia Cells in Vitro by Promoting Apoptosis. Nutrients, 12 (9), 2629; https://doi.org/10.3390/nu12092629 (WoS IF=6.7/Q1; Scopus: Q1 Food Science, Nutrition and Dietetics, SJR=1.33).
  • Toutounji M, Wanes D, El Harakeh M, El Sabban M, Rizk S, Naim HY. 2020. Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line. International Journal of Molecular Sciences, 21(8), 2726; https://doi.org/10.3390/ijms21082726 (WoS IF=6.2/Q1; Scopus: Q1 Medicine, Organic Chemistry, SJR=1.32).
  • Hoter A, Rizk S, Naim HY. 2020. Heat shock protein 60 in hepatocellular carcinoma: insights and perspectives. Frontiers in Molecular Biosciences,7, 60; https://doi.org/10.3389/fmolb.2020.00060 (WoS IF=6.1/Q1; Scopus: Q1 Biochemistry, Genetics and Molecular Biology, SJR=1.81).
  • Idriss M, Hodroj MH, Fakhoury R, Rizk S. 2020. Beta-tocotrienol exhibits more cytotoxic effects than gamma-tocotrienol on breast cancer cells by promoting apoptosis via a p53-independent PI3-kinase dependent pathway. Biomolecules, 10, 577; https://doi:10.3390/biom10040577 (WoS IF=6.1/Q2; Q1 Biochemistry and Molecular Biology, SJR=1.61).
  • Brogden G, Shammas H, Maalouf K, Walters F, Das A, Naim HY, Rizk S. 2020. Different trafficking phenotypes of Niemann-Pick C1 gene mutations correlate with various alterations in lipid storage, membrane composition and miglustat amenability. International Journal of Molecular Sciences, 21(6), 2101; https://doi.org/10.3390/ijms21062101 (WoS IF=6.2/Q1; Scopus: Q1 Medicine, Organic Chemistry, SJR=1.32).
  • El Joumaa M, Shebbo S, Taleb R, Rizk S. Borjac J. 2020. Protective effect of Matricaria chamomilla extract against 1,2-dimethylhydrazine-induced colorectal cancer in mice. Journal of Complementary and Integrative Medicine. Published online ahead of print; 20190143, eISSN 1553-3840; https://doi.org/10.1515/jcim-2019-0143 (Scopus: Q2 Complementary and alternative medicine, SJR=0.32; FWCI=4.28).
  • El Khoury M, Haykal T, Hodroj MH, Abou Najem S, Taleb R, Rizk S. 2020. Malva pseudolavatera leaf extract promotes ROS induction leading to apoptosis in Acute Myeloid Leukemia cells in vitro. Cancers 12(2), 435; https://doi.org/10.3390/cancers12020435 (WoS IF=6.6/Q1; Scopus: Q1 oncology, SJR=1.94; FWCI=1.74).
  • Ammoury C, Younes M, El Khoury M, Hodroj MH, Haykal T, Nasr P, Sily M, Sarkis R, Taleb R, Khalife R, Rizk S. 2019. The proapoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines. BMC Complementary and Alternative Medicine (currently BMC Complementary Medicine and Therapies), 19:365; https://doi.org/10.1186/s12906-019-2768-1 (WoS: IF=4.8/Q1; Scopus: Q1 Complementary and alternative medicine-SJR=0.74; FWCI=1.08).
  • Abou Najem S, Khawaja G, Hodroj MH, Babikian P, Rizk S. 2019. Adjuvant epigenetic therapy of decitabine and suberoylanilide hydroxamic acid exerts anti-neoplastic effects in acute myeloid leukemia cells. Cells 8 (12), 1480; https://doi:10.3390/cells8121480 (WoS IF=7.7/Q2 Biochemistry).
  • Ghanem P, Zouein A, Mohamad M, Hodroj MH, Haykal T, Abou Najem S, Naim HY, Rizk S. 2019. The vitamin E derivative gamma tocotrienol promotes anti-tumor effects in acute myeloid leukemia cell lines. Nutrients 11, 2808; https://doi:10.3390/nu11112808 (WoS IF=6.7/Q1; Scopus: Q1 Food Science, SJR=1.33; FWCI=0.82).
  • Hoter A, Rizk S, Naim HY. 2019. The multiple roles and therapeutic potentials of molecular chaperones in Prostate Cancer. Cancers 11(8), 1194; https://doi.org/10.3390/cancers11081194 (WoS IF=6.6/Q1; Scopus: Q1 oncology, SJR=1.94; FWCI=1.12).
  • Haykal T, Nasr P, Hodroj MH, Taleb RI, Sarkis R, El Moujabber MN, Rizk S. 2019. Annona cherimola ethanolic seed extract activates extrinsic and intrinsic apoptotic pathways in AML cells. Toxins, 11, 506; https://doi:10.3390/toxins11090506 (WoS IF=5.1/Q1; Scopus: Q1 Health, Toxicology and Mutagenesis, SJR=1.03; FWCI=1.1).
  • Hoter A, Rizk S, Naim HY. 2019. Cellular and Molecular Adaptation of Arabian Camel to Heat Stress. Frontiers in Genetics, 10:588; https://doi.org/10.3389/fgene.2019.00588 (WoS IF=4.8/Q1; Scopus: Q1 Molecular Medicine, SJR=1.47; FWCI=1.38).
  • Abou Najem S, Khawaja G, Hodroj MH, Rizk S. 2019. Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colon Cancer in Vitro. Current Molecular Pharmacology, 12 (4): 281-300; http://www.eurekaselect.com/170688 (WoS IF=3.9/Q2; Scopus: Q2 Drug Discovery, SJR=0.63; FWCI=1.75).
  • Shammas H, Kuech EM, Rizk S, Das A, Naim H. 2019. Different Niemann-Pick C1 Genotypes Generate Protein Phenotypes that Vary in their Intracellular Processing, Trafficking and Localization. Scientific Reports, 9: 1-12; https://www.nature.com/articles/s41598-019-41707-y (WoS IF=4.9/Q1; Scopus: Q1 Multidisciplinary, SJR=1.34; FWCI=1.99).
  • Hodroj MH, Abi Raad S, Jardaly A, Rizk S. 2018. Andrographolide potentiates the anti-tumor effects of Topotecan in U937 acute myeloid leukemia cells. Cancer Management and Research, vol. 10, 1079-1088; https://doi.org/10.2147/CMAR.S160924 (WoS IF=3.6/Q3; Scopus: Q2 Oncology, SJR=0.8; FWCI=1.43).
  • Barakat G, Moustafa M, Khalifeh I, Hodroj MH, Bikhazi A, and Rizk S. 2017. Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats. Journal of Physiology and Biochemistry, vol. 73(4), 623-394; https://doi.org/10.1007/s13105-017-0593-x (WoS IF=5.1/Q1; Scopus: Q1 Medicine, SJR=0.87; FWCI=0.1).
  • Khalifeh R. Hodroj MH, Fakhoury R, Rizk S. 2016. Thymoquinone from Nigella sativa Seeds Promotes the Antitumor Activity of Non-cytotoxic Doses of Topotecan in Human Colorectal Cancer Cells in Vitro. Planta Medica, vol. 82(4), 312-321; doi:10.1055/s-0035-1558289. Epub 2016 Feb 5 (WoS IF=3/Q2; Scopus: Q1 Complementary and Alternative Medicine, SJR=0.57; FWCI=1.95).
  • El Khoury N, El-Hayek S, Tarras O, El-Sibai M, El-Sabban M, Rizk S. 2014. Kefir Exhibits Anti-proliferative and Pro-apoptotic Effects on Colon Adenocarcinoma Cells with no Significant Effects on Cell Migration and Invasion. International Journal of Oncology, vol. 45, 2117-2127; doi: 10.3892/ijo.2014.2635. Epub 2014 Sep 3 (WoS IF=5.9/Q2; Scopus: Q2 Oncology and Cancer Research, SJR=1.16; FWCI=0.97).
  • Khalifeh R, El-Hayek S, Tarras O, Hodroj MH, Rizk S. 2014. The Anti-Proliferative and Pro-apoptotic Effect of Topotecan in Combination with Thymoquinone on Acute Myelogenous Leukemia. Clinical Lymphoma Myeloma and Leukemia, vol. 14, S46-55; doi: 10.1016/j.clml.2014.04.014 (WoS IF=2.8/Q3; Scopus: Q2 Hematology, SJR=0.82; FWCI=2.51).
  • Behrendt M, Krahn M, Albayati H, Amiri M, Rizk S, Naim H*. 2012. Cadherin-related protein 24 induces morphological changes and partial cell polarization by trans-interactions. Biological Chemistry, vol. 393(6), 495-503. doi: 10.1515/hsz-2011-0203 (WoS IF=3.27/Q2; Scopus: Q1 Clinical Biochemistry, SJR=1.2;).
  • Baydoun E, Mansour O, Rizk S and Brett C. 2011. Identification of EDTA-soluble polysaccharides from pea epicotyls cell walls and their interaction with xyloglucan. American Journal of Plant Sciences, vol. 2(2), 148-155.
  • Yahia N, Abu Ghazale H, Achkar A, Rizk S. 2011. Dieting Practices and Body Image perception among Lebanese University Students. Asia Pacific Journal of Clinical Nutrition, vol. 20(1), 21-28. (Q2 Medicine, Nutrition).
  • Maalouf K, Baydoun E, Rizk S. 2011. Kefir Induces Cell-cycle Arrest and Apoptosis in HTLV-1 Negative Malignant T-Lymphocytes. Cancer Management and Research, vol. 3, 39-47 (Q2 Oncology).
  • Yahia N, Abdallah A, Achkar A, Rizk S. 2010. Physical Activity, Smoking Practices, and Weight Status among Lebanese University Students. International Journal of Health Research, vol. 3 (1), 21-29. (Q3 Medicine).
  • Maalouf K, Jia J, Rizk S, Brogden G, Keiser M, Das A, Naim H. 2010. A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV. Journal of Inherited Metabolic Disease, vol. 33, 445-449. (Q2 Genetics).
  • Krahn MP, Rizk S, Alfalah M, Behrendt M and Naim HY. 2010. Protocadherin of the liver, kidney and colon associates with detergent-resistant membranes during cellular differentiation. The Journal of Biological Chemistry, vol. 285 (17), 13193-13200. (Q1 Biochemistry).
  • Rizk S, Maalouf K and Baydoun E. 2009. The Antiproliferative Effect of Kefir Cell Free Fraction on HUT-102 Malignant T-lymphocytes. Clinical Lymphoma and Myeloma, vol. 9, S198-S203. (Q2 Oncology).
  • Yahia N, Achkar A, Abdallah A, Rizk S. 2008. Eating habits and obesity among Lebanese university students. Nutrition Journal, vol. 7: 32. (Q1 Medicine, Nutrition).
  • Baydoun E, Abdel-Massih R, Dani D, Rizk S and Brett C, 2001. Galactosyl- and Fucosyl- transferases in Etiolated Pea Epicotyls: Product Identification and Subcellular Localisation. Journal of Plant Physiology, vol. 158, 145-150. (Q1 Plant Science)
  • Rizk S, Abdel-Massih R, Baydoun E and Brett C, 2000. pH-dependent Binding of Nascent Pectin and Glucuronarabinoxylan to Xylogucan in Pea. Planta, vol. 211, 423-429. (Q1 Plant Science)
  • Baydoun E, Rizk S and Brett C, 1999. Localisation of Methyltransferases involved in Glucuronoxylan and Pectin Methylation in the Golgi Apparatus in Etiolated Pea Epicotyls. Journal of Plant Physiology, vol. 155, 240-244. (Q1 Plant Science)
© Copyright 2026 Network Solutions, LLC. All rights reserved. All registered trademarks herein are the property of their respective owners.